Amniotic membrane for conjunctival reconstruction in most severe eye burns
C. Redbrake, S. Kompa, N. Schrage, R. Kuckelkorn
Background: Amniotic membrane for conjunctival reconstruction was introduced by de Rhött in 1940. In cases of most severe eye burns, conjunctiva for reconstruction is often missing. In these cases amniotic membrane might be an alternative to bucal or nasal mucosa.
Patients: In 14 eyes of 13 patients with most severe eye burns, amniotic membrane was used after symblepherolysis (n=8) and in fornix reconstruction (n=6). Follow-up time was 11,9 ± 5,7 months.
Results: 7 of 8 eyes with symblepherolysis and reconstruction with amniotic membrane were successful. In one case scarring occured again although in a smaller extend. In contrast, scarring was observed after amniotic membrane transplantation in 4 of the 6 eyes after fornix reconstruction. The mean time of scarring was 3,2 ± 2,4 months. In the missing two cases scarring was observed only partially.
In all cases the eyes calmed down after amniotic membrane transplantation.
Conclusion: Amniotic membrane transplantation is successful in the reconstruction of smaller conjunctical defects. If larger tissue defects have to be covered, nasal or buccal mucosa should be prefered. Nevertheless, amniotic membrane has a positive effect on the inflammatory status of the chronically inflammed eyes with most severe eye burns.
Dept. of Ophthalmology, RWTH Aachen, Pauwelsstr. 30, 52057 Aachen