98th Annual Meeting DOG 2000

V 314

Multifocal ERG in central areolar choroidal dystrophy

B. Feigl, A. Haas

Background: In comparison to fullfield- ERG multifocal ERG provides functional mapping of the central retina and detection of more localized defects. Central areolar choroidal dystrophy is an autosomal inherited disorder with central atrophy of the retinal pigmentepithelium and the underlying choriocapillaris. Fullfield ERG often shows only slight to moderate reductions.The purpose of our study was to investigate electroretinographic activity of the posterior pole in these patients with the multifocal ERG.

Patients and methods: We performed a multifocal ERG and a photopic fullfield ERG in 4 patients with central areolar choroidal dystrophy. 10 volunteers constituted the normal control group.

Results: In all patients reductions in amplitudes of multifocal ERG in both eyes were evident. Fullfield ERG showed decreased amplitudes in only three eyes. Subnormal amplitudes were found in 2 eyes and normal amplitudes in three eyes. Additionally ophthalmoscopic lesions were found to smaller extend than detected by the multifocal ERG.

Discussion: Multifocal ERG is a valuable tool in detecting progression of central areolar choroidal dystrophy especially when fullfied ERG responses and ophthalmoscopy are still normal.

Department of Ophthalmology, Karl- Franzenz- Universitiy, Auenbruggerplatz 4, A-8036 Graz