98th Annual Meeting DOG 2000

P 275

The determination of retinal oxygen saturation in patients with venous retinal occlusion

M. Scibor1, G. Michelson1, D. Schweitzer2, M. Hammer2, J. Harazny1

The measurement of oxygen saturation in arterioles and venoles in patients with venous retinal occlusion

The determination of oxygen saturation was performed using the imaging spectrometer, developed in Jena. Different extinction spectra of hemoglobin and oxyhemoglobin create the basis for the non-invasive estimation of the oxygen saturation. The measurements of the reflectance spectra were performed in a wavelength range from 400 nm to 700 nm. The retinal oxygen saturation was measured with an entrance slit of 1.5 mm, spectral resolution of D l < 2m, and local resolution D s < 20m m.

We measured 47 eyes of 38 healthy persons and 6 eyes of 6 patients with retinal vein occlusion.

In normals the oxygen saturation was in average 91%+-5% in retinal arterioles and 57% +-8% in retinal venoles. In patients with venous retinal occlusion the oxygen saturation was in average 90% +-5% in retinal arterioles and 25% +-11% in retinal veins.

In eyes with venous retinal occlusion we found a very significant decrease of oxygen saturation in retinal veins (25% in comparision to 57% in normals) and no significant difference in the mean oxygen saturation of retinal arterioles.

1Augenklinik mit Poliklinik, Universität Erlangen-Nürnberg, Erlangen
Augenklinik mit Poliklinik, Universität Jena, Jena