98th Annual Meeting DOG 2000

P 275

The determination of retinal oxygen saturation in patients with venous retinal occlusion

M. Scibor1, G. Michelson1, D. Schweitzer2, M. Hammer2, J. Harazny1

Purpose:
The measurement of oxygen saturation in arterioles and venoles in patients with venous retinal occlusion

Method:
The determination of oxygen saturation was performed using the imaging spectrometer, developed in Jena. Different extinction spectra of hemoglobin and oxyhemoglobin create the basis for the non-invasive estimation of the oxygen saturation. The measurements of the reflectance spectra were performed in a wavelength range from 400 nm to 700 nm. The retinal oxygen saturation was measured with an entrance slit of 1.5 mm, spectral resolution of D l < 2m, and local resolution D s < 20m m.

We measured 47 eyes of 38 healthy persons and 6 eyes of 6 patients with retinal vein occlusion.

Results:
In normals the oxygen saturation was in average 91%+-5% in retinal arterioles and 57% +-8% in retinal venoles. In patients with venous retinal occlusion the oxygen saturation was in average 90% +-5% in retinal arterioles and 25% +-11% in retinal veins.

Conclusions:
In eyes with venous retinal occlusion we found a very significant decrease of oxygen saturation in retinal veins (25% in comparision to 57% in normals) and no significant difference in the mean oxygen saturation of retinal arterioles.

1Augenklinik mit Poliklinik, Universität Erlangen-Nürnberg, Erlangen
2
Augenklinik mit Poliklinik, Universität Jena, Jena



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